
Hey {{first_name|default:there}}, itโs Vadim ๐
Quick note before we dive in - in case you missed it, I launched the Pitch Deck Audit earlier this week.
It's a focused 1:1 session to get your deck and investor story dialed in before you go live.
There's a launch offer running right now that was going to expire at midnight tonight, but I'm extending it one more day, until midnight tomorrow (Monday). If you've been thinking about it or missed the announcement, check it out here:
Now, onto today's issue.
There's a question that comes up in almost every conversation I have with founders. Sometimes it's stated directly. More often it's beneath the surface of questions that sound like this:
โHow do I get investors to actually respond?โ
โHow do I find and secure a lead investor?โ
โHow do I know when to push and when to wait?โ
โHow do I align my fundraising timeline with where my science actually is?โ
All of these are real questions. They come up in my inbox, in coaching calls, and straight from your survey responses.
But when I sit with them, they almost always point to the same underlying tension:
How do I, as a founder, have real ownership over my fundraise - and build momentum and urgency, without saying anything that's not true, and without feeling like I'm being pushy or salesy?
Here's what I've found: most founders are actually asking the wrong question.
The right question is not: โHow do I manufacture urgency?โ
The right question is: โHow do I run a process where urgency and momentum are built into the structure - so I can be in as much control as the current environment allows?โ
That's what we're tackling today.
๐งญ HEREโS WHAT WEโLL COVER:
The current state of biotech fundraising timelines
The 3-Phase Fundraising Framework
The โcampaign windowโ and how to run a tight round without feeling pushy
Scripts, bonus resources, and more!
Letโs dive in!
FOUNDER STORY
When does a fundraise end, if it never officially started?
A founder came to me last year, about 11 months into what he called his โfundraising process.โ
He and his team had the basics covered - great presentation, good story, strong science, a team that had seen success in an adjacent space.
But - no advanced conversations, no term sheet. Not even a partner meeting in the last four months.
When I asked him to walk me through his process, hereโs what I heard:
Heโd had a great first meeting with a fund back in the spring. Theyโd asked for monthly updates. Heโd been sending them. He was โbuilding the relationship.โ
Heโd taken an intro to a family office that a mutual contact had offered. The conversation went well. Theyโd said theyโd love to reconnect โwhen the data matures a bit.โ
Heโd had maybe 20 conversations in 11 months. Each one carefully sequenced. Each one treated as a long-term relationship investment.
I asked him: when did you officially launch the round?
He paused. โI meanโฆ Iโve been raising since last April.โ
That was the problem. Heโd been warming up for 11 months and never flipped the switch.
His fundraise was open without having a defined window, a specific ask, and a target close date.
To investors, the opportunity felt evergreen.
So we redesigned his approach. We organized his contacts into a priority list. Mapped out who had warm intro paths. Set a 10-week window to run the actual campaign.
Within six weeks of launching properly, he was having serious conversations with fund partners, with two progressing to real due diligence.
The science didnโt change. The investors didnโt change. Most of them were already in his network.
The process did.
Thatโs what weโre going to break down today.
FRAMEWORK
The 3-Phase Fundraising Map
The current state of fundraising
Letโs start by acknowledging what you probably already know: biotech fundraising takes a long time, and itโs been taking longer over the past several years than in the ZIRP days of 2020-2021.
The median time between rounds in healthcare is also more prolonged - now around 760 days (about 2.1 years), according to Carta. Investors are raising bigger funds but writing fewer checks.
As a result, decision cycles are longer. If your raise is taking more time than you expected, thatโs not always a reflection of your company. We are in a genuinely challenging environment, and that needs to be accounted for.
But hereโs what the data doesnโt show you: a well-run raise still takes 9-15 months. The raises dragging on for 18-24+ months usually have a common root cause - either they started prematurely, or, more likely, they are not organized in phases.
The three phases of a successful fundraise
Most founders think of fundraising as one continuous activity. It isnโt. A well-run raise has three distinct phases with different objectives, different activities, and very different timelines. Collapsing them into one murky โfundraising modeโ is exactly what turns a 12-month raise into a 24-month one.
Phase 1: The warm-up
This is where you build the relationship capital. You attend conferences, pursue warm intros, have exploratory conversations over coffee. Youโre letting investors watch you make progress before you ever make an ask.
The key move: be explicit that youโre not raising yet.
โWeโre planning to open our round in Q[X] - I wanted to connect now so you have context before weโre live.โ
That one sentence plants a seed and sets up Phase 2 in a clean and organic way.
The trap: never leaving Phase 1. Staying in warm-up mode indefinitely feels safe - no risk of rejection. But thereโs also no path to a close. At some point, you have to flip the switch.
Phase 2: The campaign window
This is the round and the โliveโ campaign.
This is where you flip the switch and go from exploring to executing.
The defining feature: conversations run in parallel, not sequentially. Many founders, especially those running their first fundraise, talk to one investor at a time, waiting to hear back before moving to the next.
This is the single biggest time killer. No parallel pipeline means no momentum, no cross-signal, no leverage. Youโre always waiting.
In a well-run campaign window:
Your highest-priority contacts go out in week 1. Warm intros fire at the same time.
Every conversation ends with a specific next step and a date. Not โletโs stay in touch.โ
You have a soft close target - a real internal deadline, not a bluff, that focuses everyoneโs energy including yours.
Youโre making fast decisions: who gets diligence materials, who gets a second meeting, who gets a respectful pass.
The window creates honest urgency. Not manufactured pressure - just the reality of a founder whoโs running a real process.
Phase 3: Diligence & Close (6-10 weeks from first term sheet)
This involves legal, due diligence, cap table review, and final negotiations. This phase may be largely out of your control in terms of pace.
However, what IS in your control is how prepared you walk in.
A clean data room, an organized cap table, and a clear use-of-funds narrative tied to milestones can compress this phase significantly.
Founders who go in unprepared routinely add 4-6 weeks to their close - and occasionally watch deals fall apart in that gap.
Add it up: a well-run raise takes 9-15 months
The difference almost always comes down to one thing: whether the founder ever actually entered Phase 2.
PRO TIP
The monthly investor update
Iโve talked about this before, but I keep bringing it up because Iโm genuinely surprised by how few founders actually do it - especially during a live fundraise.
This update is not for your existing investors; itโs for your prospective ones.
Hereโs how you can execute on this:
During Phase 1, when youโre in relationship-building mode, ask the investor a simple question before you wrap up:
โWould you mind if I kept you posted on our progress as we build toward our raise?โ
Almost everyone says yes. Youโre not asking for anything. Youโre offering something.
Then you add them to a short monthly email. Keep it to 150โ250 words.
Hereโs what to include:
During Phase 1 (company updates):
A milestone you hit - preclinical result, regulatory filing, partnership signed
A key hire or advisor who joined
A conference you presented at or an award you won
During Phase 2 (fundraise updates):
โWe opened our round officially this month and have had strong early interestโ
โWe presented at [event] and had several follow-up conversations from itโ
โWeโve secured our first angel commitments and are in diligence conversations with a small number of fundsโ
โWeโre targeting a close by end of Q[X] and are prioritizing conversations with aligned investorsโ
Youโre not pressuring anyone. Youโre keeping them informed - which is exactly what a good investor communication looks like.
The obvious benefit is momentum. By the time you officially ask for a meeting in Phase 2, theyโve been watching you execute for months. The ask feels natural, not cold.
But the less obvious benefit is what it signals about you as a founder. If youโre this disciplined about keeping prospective investors informed when you donโt even have their money yet, what does that tell them about how youโll communicate once they do invest?
Youโre showing them that youโre the kind of founder who does what they say theyโll do. In a world full of founders who disappear between meetings, that alone is memorable.
One note on format: send it from your personal email, not a bulk email tool, even if that means setting aside a few hours on the weekend to send the updates. Remember - the goal is to build real, authentic, human relationships with individuals and funds that may be with you for the life of your company.
The goal here is not marketing campaign efficiency, its old school human authenticity.
An added bonus
90% of these updates should be just that - updates, with no ask attached.
But since you're essentially building a warm rolodex of people who know your work, once in a while it's completely appropriate to include a gentle ask.
Looking for a specific hire? A connection at a BD team inside a large pharma? A distributor in a new market?
These are exactly the kinds of things your prospective investor network can help with - and asking makes you more human, not less professional.
REALITY CHECK
This framework is aspirational - and thatโs the point
Now that I shared the perfect fundraising template, I want to recognize something - fundraising rarely happens in a perfect template, of any kind ๐
If youโre reading this, you probably already know - fundraising is messy.
It rarely follows a clean three-phase arc.
Investors go dark. Or they just go to the Maldives.
Data readouts shift timelines.
Key intro paths fall through. Life happens.
And this is especially true right now. All in all, itโs a genuinely difficult environment to raise in, and we certainly shouldnโt pretend otherwise.
So this framework isnโt here to make you feel like youโve failed if your raise doesnโt follow a clean template. And itโs definitely not a checklist to grade yourself against.
What Iโve found is that an aspirational plan gives you a picture of what โgoodโ looks like.
And when the inevitable chaos hits, that picture becomes a north star.
It gives you something to navigate back toward, rather than just reacting to whatever comes next.
So, know that you donโt have to run a perfect campaign. You just need enough structure to know when youโve drifted too far from one - and what to do about it.
At the end of the day - itโs better to have a plan thatโs aspirational than no plan at all.
Iโm pretty sure it was someone famous that said this? :)
BONUS RESOURCE
Phrases to create momentum without creating pressure
If you've ever stared at a follow-up draft wondering whether it sounds too pushy or too passive, I hope this can serve as a helpful starting point.
Opening a first meeting with a window built in:
โWeโre planning to open our round formally in [month]. I wanted to connect now so you have real context before weโre live - and so I can understand whether this fits what youโre looking for.โ
Following up after a strong first meeting:
โReally appreciated the conversation. Iโll send over our deck and data room access by [day]. Weโre running a few conversations in parallel right now - would [specific date] work to reconnect and answer any questions?โ
Responding to โletโs stay in close touchโ:
โIโd love that. Weโre targeting [soft close date] for this round - would it make sense to reconnect in [2โ3 weeks] once youโve had a chance to review the materials?โ
When an investor says โthe timing isn't right for us right nowโ: โCompletely understand, timing matters. We're planning to run another process in [approximate timeframe] once we hit [next milestone]. Would it be okay if I looped back in when we're closer to that? I'd want you to have a first look.โ
Sharing a milestone to re-engage a warm contact before going live: โWanted to share a quick update before we officially open the round - we just [hit milestone]. Given our earlier conversation, I thought you'd want to see this before we're formally live. Happy to reconnect if the timing works.โ
Communicating honest momentum once the round is moving: โWanted to give you a quick update - we've had a strong first few weeks and have a several conversations that have progressed to term sheet discussions. We're still in conversations with a small number of investors we're excited about and wanted to make sure you had the full picture before we get further along.โ
After a partner meeting, checking on next steps without hovering: โReally appreciated the time with the team last week. I know decisions move at their own pace, so I just wanted to stay in sync on timing. We're targeting a close by [date] and I'd love to know where this lands for you before we get further along. What would be helpful from my end?โ
When an investor keeps asking for more before committing: โHappy to keep going deeper, I want you to have everything you need. That said, I want to be transparent: we're planning to finalize our lead by [date] so we can close the round on schedule. What would need to be true for you to feel ready to move forward by then?โ
THATโS A WRAP!
Hereโs my challenge for you this week:
Figure out which phase youโre actually in. Be honest.
If you're still in early planning mode - that's not a bad thing.
Now you have a roadmap. You know what the phases look like, what to do in each one, and what gears to move through from zero to term sheet.
You can start Phase 1 with intention instead of stumbling into it.
If you've been โfundraisingโ for more than six months without a defined window, a parallel pipeline, and a soft close target - you're in Phase 1. And that's okay. Now you know.
The question is: when are you flipping the switch? And what do you need to progress to Phase 2?
Hit reply - I'd love to hear where you are in the process and what's holding you back. These replies genuinely help me figure out what to cover next.
See you next Sunday!
- Vadim
PS: When youโre ready, hereโs how I can help:
Work with me directly. Whether it's fundraising, pharma partnerships, or building your founder brand - I help early-stage biotech founders get investor-ready and visible. If any of these resonate, I'd love to hear from you.
Join the Investor List Accelerator waitlist. A 5-week intensive where I'll walk you through the SIFT methodology to build a qualified, tiered investor list tailored to your company - so you stop pitching funds that will never write you a check.